The American luxury car market has been experiencing strange trends in 2025, with some brands suffering from a decline in sales figures, while others are setting new volume records. Regardless of performance, the entire luxury segment is struggling with competitive pricing. Modern options are exponentially more expensive compared to those sold just three years ago, due to several key factors. This has also resulted in new-generation luxury cars suffering from some of the worst depreciation rates that the market has ever seen.
This means that if you’re happy to buy a slightly used luxury car, you’re going to benefit from some of the best deals that you can enjoy. Naturally, reliability remains a noteworthy concern when shopping in the used car market, but there are some luxury options that currently hold high reliability standards, making them viable choices if you need something that’s dependable without compromising on overall quality and comfort.
The models in this list are ranked by their iSeeCars reliability rating and are ordered from worst to best.
2022 Audi A7
Reliability Score: 7.5/10
We start our list off with the 2022 Audi A7, which iSeeCars issues a 7.5/10 reliability score, indicating that it will last 10.5 years or 119,036 miles with a 1.5-percent probability of reaching 200,000 miles. Edmunds suggests that the 2022 A7 will cost you $83,839 to own over five years and 60,000 miles, $10,932 of which accounts for maintenance and $8,283 for repairs.
Pricing for the now-defunct Audi A7 started at $72,000 when new. Expect it to lose $43,888 or 61 percent of its value after five years and 60,000 miles, which is one of the worst depreciation rates that you will get to see on this list.
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2022 Infiniti Q50
Reliability Score: 7.7/10
iSeeCars awards the 2022 Infiniti Q50 range with a 7.7/10 reliability score, suggesting that the premium Japanese sedan will cover 12.6 years or 142,146 miles without facing any noteworthy mechanical issues, with a 13 percent probability of hitting 200,000 miles. J.D. Power issues the 2022 Q50 with an 80/100 consumer-verified overall score, consisting of 75/100 for the driving experience, 80/100 for resale, and 84/100 for the dealership experience.
When new, you would have paid $42,100 for the base Infiniti Q50 derivative. These models typically sell for anywhere between $29,331 and $43,254 as of today. The 2022 Q50 is likely to lose $23,692 or 55 percent of its value after five years and 60,000 miles. According to Edmunds, you can expect a 2022 Q50 to cost you $64,291 to own over five years, which includes $9,192 on maintenance and $3,588 on repairs.
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2022 Audi A4
Reliability Score: 7.7/10
The 2022 Audi A4 sedan and Avant scores 7.7/10 on the iSeeCars reliability test, which indicates it will have an average mechanical lifespan of 12 years and 129,982 miles, with a 7.2-percent probability of reaching 200,000 miles. It also gets a 78/100 consumer-verified overall score from J.D. Power, which includes 76/100 for the driving experience, 79/100 for resale, and 78/100 for the dealership experience.
Pricing for this model started at $39,900 when it was new in 2022. The range typically sells for $22,373 to $30,724 on the used market today. You can expect the ’22 A4 to lose $23,114 or 55 percent of its value within five years and 60,000 miles of ownership. A 2022 Audi A4 is expected to cost you $61,814 to own over five years, consisting of $10,501 on maintenance and $7,139 on repairs.
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2022 Mercedes-Benz CLS
Reliability Score: 7.7/10
iSeeCars issues the 2022 Mercedes-Benz CLS range with a 7.7/10 reliability score, but it hands it an average lifespan estimate of 9.1 years or 94,309 miles with a 0.8-percent probability of reaching 200,000 miles. Edmunds highlights that you’ll spend $84,748 on a five-year ownership experience, including $12,887 on maintenance and $9,820 on repairs.
Pricing for the CLS started at $72,950 when new. Today, you’re likely to pick one up for anywhere between $44,661 and $53,787, depending on mileage, condition, and specification.
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2022 Mercedes-Benz CLA
Reliability Score: 7.7/10
The 2022 Mercedes-Benz CLA fares a bit better than its larger sibling on the reliability front, with iSeeCars issuing it with a 13.4-year and 130,442-mile average lifespan estimate and a 9.2 percent probability of reaching 200,000 miles. This results in it earning a 7.7/10 reliability score. A three-year-old CLA will cost you $62,814 to own over five years, with maintenance estimated at $9,570 and repairs at $8,689.
A new CLA would have cost you $38,200 when new in 2022. They typically sell for $26,961 to $48,469, but this range includes the AMG variants. You can expect it to lose $20,910 or 47.1 percent of its value after five years and 60,000 miles.
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2022 BMW 2 Series
Reliability Score: 7.8/10
We’re including the BMW 2 Series Coupe and Gran Coupe in this entry because they feature the same 7.8/10 reliability score, despite them being two different model lines. For the Coupe, iSeeCars indicates that you can expect a 14-year or 121,645-mile average lifespan with a 5.5-percent probability of reaching 200,000 miles. J.D. Power issues the 2022 2 Series range with an impressive 82/100 consumer-verified overall score. This includes 83/100 for the driving experience, 82/100 for resale, and 80/100 for the dealership experience.
The would have cost you $35,700 when new, while the 230i Coupe would have set you back by $36,350. Both bodystyles sell for anywhere between $24,591 and $45,472 three years later. Expect the Coupe to lose $21,081 or 53.2 percent of its value after five years and 60,000 miles. Edmunds suggests that the 230i Coupe will cost $63,669 to own over five years, including $11,985 on maintenance and $8,689 on repairs.
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2022 Mercedes-Benz C-Class
Reliability Score: 7.9/10
The 2022 Mercedes-Benz C-Class range holds a 7.9/10 reliability rating from iSeeCars, based on an average lifespan valuation of 12.6 years or 116,386 miles with a 4.5-percent probability of reaching 200,000 miles. $63,669 is what you can expect to spend on a C-Class ownership experience, which includes $11,985 on maintenance and $8,689 on repairs.
The base C300‘s pricing started at $43,550 when it was new three years ago. Three-year-old models will sell for anywhere between $30,163 and $71,813, but this also includes the AMG variants. Expect the C-Class to lose $25,436 or 52.5 percent of its value after five years and 60,000 miles.
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2022 Lexus ES 350
Reliability Score: 7.9/10
iSeeCars awards the 2022 Lexus ES 350 a 7.9/10 reliability rating, but it doesn’t give us a valuation for its average lifespan. Regardless, the ES has a longstanding reputation for covering great distances before you face any mechanical issues, if ever. J.D. Power awards this model with an 83/100 consumer-verified overall score, including 88/100 for quality and reliability, 77/100 for the driving experience, 76/100 for resale, and 85/100 for the dealership experience.
The premium Japanese brand started this model’s pricing off at $40,950 when it was new in 2022. They typically sell for around $29,973 to $43,214 today. The Lexus ES is likely to lose $17,684 or 24.1 percent of its value within five years and 60,000 miles. Edmunds suggests that you’ll spend $57,199 on a 2022 ES, which includes $8,166 on maintenance and $3,145 on repairs.
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2022 Mercedes-Benz E-Class
Reliability Score: 8.3/10
All bodystyles of the 2022 Mercedes-Benz E-Class benefit from an impressive 8.3/10 reliability rating from iSeeCars. The wagon benefits from the highest average lifespan standard of 13.8 years and 144,034 miles, with a 16.7-percent probability of reaching 200,000 miles. J.D. Power awards the model with a 78/100 consumer-verified overall score, which includes 81/100 for quality and reliability, 74/100 for the driving experience, 77/100 for resale, and 79/100 for the dealership experience.
The E350 sedan was the cheapest model you could buy in 2022, with its $54,950 MSRP. The range now sells for $34,425 to $90,882, if you include the AMG variants. Expect this model to lose $35,555 or 56.9 percent of its value after five years and 60,000 miles. This will cost you $72,462 to own over five years, which includes $9,033 on maintenance and $8,689 on repairs.
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2022 Lexus IS 350
Reliability Score: 8.5/10
According to iSeeCars, the 2022 Lexus IS 350 is the most reliable three-year-old luxury car you can buy, with an 8.5/10 reliability score. The publication indicates that this model covers 16.9 years or 182,995 miles before facing any serious mechanical issues with a 39.8-percent probability of reaching 200,000 miles. The 2022 Lexus IS range benefits from an 86/100 consumer-verified overall score, consisting of 91/100 for quality and reliability, 81/00 for the driving experience, 84/100 for resale, and 85/100 for the dealership experience.
You would have found yourself paying $39,125 for a new model in 2022. These now sell for $36,282 to $67,410, depending on the specification, condition, and mileage. This price range also includes the IS 500 F Sport, which would have cost as much as $70,200 if you opted for the Ultimate Edition. On the depreciation front, you can expect to lose $16,590 or 41.3 percent of this premium Japanese sedan’s value after five years and 60,000 miles.
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Sources: iSeeCars, J.D. Power, KBB